Affordable Access

deepdyve-link
Publisher Website

Genomes in the clinic: the Gustave Roussy Cancer Center experience

Authors
  • Lacroix, Ludovic
  • Boichard, Amelie
  • André, Fabrice
  • Soria, Jean-Charles1, 2, 3, 4, 5
  • 1 Gustave Roussy, Translational Research Laboratory and Biobank
  • 2 Gustave Roussy, Inserm U981
  • 3 Gustave Roussy, Department of Medical Biology and Pathology
  • 4 Gustave Roussy, Department of Medical Oncology
  • 5 Gustave Roussy, Drug Development Department
Type
Published Article
Journal
Current Opinion in Genetics & Development
Publisher
Elsevier
Publication Date
Jan 01, 2014
Accepted Date
Nov 17, 2013
Volume
24
Pages
99–106
Identifiers
DOI: 10.1016/j.gde.2013.11.013
Source
Elsevier
License
Unknown

Abstract

The extensive molecular characterization of tumors with high throughput technologies has led to the segmentation of different tumors into very small molecularly defined subgroups. Many ongoing clinical trials are conducted only when specific molecular alterations are identified in tumor samples. In this review, we will describe the implementation of genome analysis in the clinical setting as it has expanded over the last four years in our Precision Medicine Program. This manuscript will also highlight the main limitations and challenges related to the development of broader and deeper genome analysis.

Report this publication

Statistics

Seen <100 times