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Genome-wide association study identifies CAMKID variants involved in blood pressure response to losartan: the SOPHIA study.

Authors
  • Frau, Francesca
  • Zaninello, Roberta
  • Salvi, Erika
  • Ortu, Maria Francesca
  • Braga, Daniele
  • Velayutham, Dinesh
  • Argiolas, Giuseppe
  • Fresu, Giovanni
  • Troffa, Chiara
  • Bulla, Emanuela
  • Bulla, Patrizia
  • Pitzoi, Silvia
  • Piras, Daniela Antonella
  • Glorioso, Valeria
  • Chittani, Martina
  • Bernini, Giampaolo
  • Bardini, Michele
  • Fallo, Francesco
  • Malatino, Lorenzo
  • Stancanelli, Benedetta
  • And 22 more
Type
Published Article
Journal
Pharmacogenomics
Publication Date
Sep 01, 2014
Volume
15
Issue
13
Pages
1643–1652
Identifiers
DOI: 10.2217/pgs.14.119
PMID: 25410890
Source
Medline
Keywords
License
Unknown

Abstract

Using a genome-wide approach, we identified the CAMK1D gene as a novel locus associated with blood pressure response to losartan. CAMK1D gene characterization may represent a useful tool to personalize the treatment of essential hypertension.

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