Genome evolution in yeasts.

Bernard Dujon; David Sherman; Gilles Fischer; Pascal Durrens; Serge Casaregola; Ingrid Lafontaine; Jacky De Montigny; Christian Marck; Cécile Neuvéglise; Emmanuel Talla; Nicolas Goffard; Lionel Frangeul; Michel Aigle; Véronique Anthouard; Anna Babour; Valérie Barbe; Stéphanie Barnay; Sylvie Blanchin; Jean-Marie Beckerich; Emmanuelle Beyne; Claudine Bleykasten; Anita Boisramé; Jeanne Boyer; Laurence Cattolico; Fabrice Confanioleri; Antoine De Daruvar; Laurence Despons; Emmanuelle Fabre; Cécile Fairhead; Hélène Ferry-Dumazet; Alexis Groppi; Florence Hantraye; Christophe Hennequin; Nicolas Jauniaux; Philippe Joyet; Rym Kachouri; Alix Kerrest; Romain Koszul; Marc Lemaire; Isabelle Lesur; Laurence Ma; Héloïse Muller; Jean-Marc Nicaud; Macha Nikolski; Sophie Oztas; Odile Ozier-Kalogeropoulos; Stefan Pellenz; Serge Potier; Guy-Franck Richard; Marie-Laure Straub; Audrey Suleau; Dominique Swennen; Fredj Tekaia; Micheline Wésolowski-Louvel; Eric Westhof; Bénédicte Wirth; Maria Zeniou-Meyer; Ivan Zivanovic; Monique Bolotin-Fukuhara; Agnès Thierry; Christiane Bouchier; Bernard Caudron; Claude Scarpelli; Claude Gaillardin; Jean Weissenbach; Patrick Wincker; Jean-Luc Souciet

Genome evolution in yeasts.

Authors

Dujon, Bernard
Sherman, David
Fischer, Gilles
Durrens, Pascal
Casaregola, Serge
Lafontaine, Ingrid
De Montigny, Jacky
Marck, Christian
Neuvéglise, Cécile
Talla, Emmanuel
Goffard, Nicolas
Frangeul, Lionel
Aigle, Michel
Anthouard, Véronique
Babour, Anna
Barbe, Valérie
Barnay, Stéphanie
Blanchin, Sylvie
Beckerich, Jean-Marie
Beyne, Emmanuelle
Bleykasten, Claudine
Boisramé, Anita
Boyer, Jeanne
Cattolico, Laurence
Confanioleri, Fabrice
De Daruvar, Antoine
Despons, Laurence
Fabre, Emmanuelle
Fairhead, Cécile
Ferry-Dumazet, Hélène
Groppi, Alexis
Hantraye, Florence
Hennequin, Christophe
Jauniaux, Nicolas
Joyet, Philippe
Kachouri, Rym
Kerrest, Alix
Koszul, Romain
Lemaire, Marc
Lesur, Isabelle
Ma, Laurence
Muller, Héloïse
Nicaud, Jean-Marc
Nikolski, Macha
Oztas, Sophie
Ozier-Kalogeropoulos, Odile
Pellenz, Stefan
Potier, Serge
Richard, Guy-Franck
Straub, Marie-Laure
Suleau, Audrey
Swennen, Dominique
Tekaia, Fredj
Wésolowski-Louvel, Micheline
Westhof, Eric
Wirth, Bénédicte
Zeniou-Meyer, Maria
Zivanovic, Ivan
Bolotin-Fukuhara, Monique
Thierry, Agnès
Bouchier, Christiane
Caudron, Bernard
Scarpelli, Claude
Gaillardin, Claude
Weissenbach, Jean
Wincker, Patrick
Souciet, Jean-Luc

And 47 more

Type

Published Article

Journal

Nature

Publisher

Springer Nature

Publication Date

Jul 01, 2004

Volume

430

Issue

6995

Pages

35–44

Identifiers

PMID: 15229592

Source

Medline

License

Unknown

Abstract

Identifying the mechanisms of eukaryotic genome evolution by comparative genomics is often complicated by the multiplicity of events that have taken place throughout the history of individual lineages, leaving only distorted and superimposed traces in the genome of each living organism. The hemiascomycete yeasts, with their compact genomes, similar lifestyle and distinct sexual and physiological properties, provide a unique opportunity to explore such mechanisms. We present here the complete, assembled genome sequences of four yeast species, selected to represent a broad evolutionary range within a single eukaryotic phylum, that after analysis proved to be molecularly as diverse as the entire phylum of chordates. A total of approximately 24,200 novel genes were identified, the translation products of which were classified together with Saccharomyces cerevisiae proteins into about 4,700 families, forming the basis for interspecific comparisons. Analysis of chromosome maps and genome redundancies reveal that the different yeast lineages have evolved through a marked interplay between several distinct molecular mechanisms, including tandem gene repeat formation, segmental duplication, a massive genome duplication and extensive gene loss.

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. This record was last updated on 07/03/2016 and may not reflect the most current and accurate biomedical/scientific data available from NLM. The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/15229592

Report this publication

Statistics

Seen <100 times