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The genetics of protein secretion in E. coli.

Authors
  • Bieker, K L1
  • Silhavy, T J
  • 1 Department of Molecular Biology, Princeton University, NJ 08544.
Type
Published Article
Journal
Trends in Genetics
Publisher
Elsevier
Publication Date
Oct 01, 1990
Volume
6
Issue
10
Pages
329–334
Identifiers
PMID: 2281528
Source
Medline
License
Unknown

Abstract

Genetic studies have identified six genes whose products comprise the general protein secretion machinery of Escherichia coli. Insights from mutant analysis and the biochemical properties of the purified components allows the secretion pathway to be described in some detail. The picture emerging provides a useful paradigm for similar pathways in other organisms.

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