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Genetic relatedness of the neuramindase of influenza A strains Nav2, Nav3, and Nav6.

Authors
  • Scholtissek, C
  • Rott, R
  • Lvov, D K
  • Myasnikova, I A
Type
Published Article
Journal
Archives of virology
Publication Date
Jan 01, 1980
Volume
65
Issue
3-4
Pages
325–328
Identifiers
PMID: 7416973
Source
Medline
License
Unknown

Abstract

By molecular hybridization and by neuraminidase inhibition tests it is shown that all influenza A strains tested carrying an Nav3 or Nav2 neuraminidase (NA) are genetically highly related in their NA genes and cross-react serologically with specific antineuraminidase sera. The Nav6 strains exhibit a very low RNase protection after hybridization and do not cross-react serologically with Nav2 or Nav3 strains. Thus, the Nav2 and Nav3 strains comprise one group which is distinct from that of Nav6 strains.

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