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Genetic Investigation of Uterine Carcinosarcoma: Case Report and Cohort Analysis.

Authors
  • Hembree, Timothy N
  • Teer, Jamie K
  • Hakam, Ardeshir
  • Chiappori, Alberto A1
  • 1 Department of Thoracic Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA. [email protected]
Type
Published Article
Journal
Cancer control : journal of the Moffitt Cancer Center
Publication Date
Jan 01, 2016
Volume
23
Issue
1
Pages
61–66
Identifiers
PMID: 27009459
Source
Medline
License
Unknown

Abstract

Disease stage alone predicted the rate of clinical survival. Up to 50% in the study group were identified at having early stage disease (stage 1/2), indicating improved rates of overall detection compared with previously reported data. Our mutational analysis findings add to the number of tumors in which these mutations have been found and suggest that chromatin-remodeling dysregulation may play a role in the tumorigenesis of carcinosarcoma.

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