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Genetic diversity of Legionella pneumophila inferred from rpoB and dotA sequences.

Authors
  • Ko, K S
  • Miyamoto, H
  • Lee, H K
  • Park, M-Y
  • Fukuda, K
  • Park, B J
  • Kook, Y-H
Type
Published Article
Journal
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
Publication Date
Mar 01, 2006
Volume
12
Issue
3
Pages
254–261
Identifiers
PMID: 16451413
Source
Medline
License
Unknown

Abstract

This study characterised the population structure of Legionella pneumophila by comparing the rpoB (300-bp) and dotA (360-bp) sequences of 267 isolates (18 reference strains, 149 Korean isolates and 100 Japanese isolates). In addition to the six clonal subgroups established previously, four subgroups, P-V to P-VIII, were identified. Subgroupings based on rpoB and dotA sequences were found to correlate with the source of the isolates, and this data may be useful for future epidemiological studies. Fourteen (five Korean and nine Japanese) isolates showed incongruent subgroupings in the rpoB and dotA trees, suggesting that genetic exchange among subgroups, and even among subspecies, may occur frequently in nature.

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