Affordable Access

deepdyve-link
Publisher Website

The Genetic Diversity of HIV-1 Within Antiretroviral-Naive Outpatients in Ganzhou, China.

Authors
  • Xie, Ying-Na1
  • Zhang, Yu-Ning1
  • Cheng, Si-Wei2
  • Huang, Dan-Dan1
  • Xie, Bing-Yu1
  • Huang, Zhen1
  • Zhou, Yan-Heng2
  • Zhu, Da-Qing3
  • Chen, Xin1
  • 1 Department of Pathogenic Biology, School of Basic Medical Sciences, Gannan Medical University, Ganzhou, China. , (China)
  • 2 Department of Zoology, School of Life Sciences, Yan'an University, Yan'an, China. , (China)
  • 3 Department of Infectious Disease, Fifth People's Hospital of Ganzhou, Ganzhou, China. , (China)
Type
Published Article
Journal
AIDS Research and Human Retroviruses
Publisher
Mary Ann Liebert
Publication Date
Feb 01, 2021
Volume
37
Issue
2
Pages
147–150
Identifiers
DOI: 10.1089/AID.2020.0168
PMID: 32799642
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

To explore the molecular epidemiological status of human immunodeficiency virus type 1 (HIV-1) in Ganzhou, China, eight HIV-1-positive outpatients were recruited from July 5 to 21, 2018. Six HIV-1 near-full-length sequences were amplified and sequenced from the plasma samples that were collected before the patients' antiretroviral treatments. Phylogenetic and bootscan analyses revealed that one of the sequences was CRF01_AE, one was CRF55_01B, and two were CRF07_BC. Notably, one of the sequences was a unique recombinant form, and one of them was a second-generation recombinant form of CRF07_BC and subtype C. These results revealed that multiple HIV-1 subtypes are circulating in Ganzhou, China. Systematic surveys with large sample sizes are urgently needed to explore the exact molecular epidemiological characteristics and to trace the origins of HIV-1 in Ganzhou, China.

Report this publication

Statistics

Seen <100 times