Affordable Access

The genetic control of virulence in group A streptococci. I. Conjugal transfer of plasmids and their effect on expression of some host cell properties.

Authors
  • Ravdonikas, L E
Type
Published Article
Journal
Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology
Publication Date
Feb 01, 1983
Volume
91
Issue
1
Pages
55–60
Identifiers
PMID: 6346792
Source
Medline
License
Unknown

Abstract

Transfer of five plasmids was studied in 30 different mating systems, involving streptococci of groups A, D and H. The erythromycin resistance marker (Emr) of all five plasmids was transferable at frequencies ranging from 8 X 10(-7) to 2 X 10(-4). All original donor strains except SM60 (pERL1) contained phage activity, but evidence was obtained favouring conjugation over transduction as the mechanism of transfer. The process was rec-independent. The transconjugants were able to serve as donors of the Emr-marker in secondary matings. A shortened derivate (pSM10) of the plasmid pSM10419 could also be transferred. Finally, the presence of the plasmid pSM15346 influenced the expression of the capacity to adhere to human epithelial cells and the resistance to UV-light of the host, whereas anti-phagocytic activity and production NADse and of opacity factor was unaffected by the plasmid.

Report this publication

Statistics

Seen <100 times