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Genetic characterization of a betanodavirus isolated from a clinical disease outbreak in farm-raised tilapia Oreochromis niloticus (L.) in Thailand.

Authors
  • Keawcharoen, J
  • Techangamsuwan, S
  • Ponpornpisit, A
  • Lombardini, E D
  • Patchimasiri, T
  • Pirarat, N
Type
Published Article
Journal
Journal of fish diseases
Publication Date
Jan 01, 2015
Volume
38
Issue
1
Pages
49–54
Identifiers
DOI: 10.1111/jfd.12200
PMID: 24164433
Source
Medline
Keywords
License
Unknown

Abstract

Betanodavirus infection was diagnosed in larvae of farm-raised tilapia Oreochromis niloticus (L.), in central Thailand. Extensive vacuolar degeneration and neuronal necrosis were observed in histological sections with positive immunohistochemical staining for betanodavirus. Molecular phylogenetic analysis was performed based on the nucleotide sequences (1333 bases) of the capsid protein gene. The virus strain was highly homologous (93.07-93.88%) and closely related to red-spotted grouper nervous necrosis virus (RGNNV).

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