Generating novel polyene antifungal drugs.
Instituto de Biotecnología INBIOTEC, Parque Científico de León y Area de Microbiología, Facultad de Biología, Universidad de León, 24071 León, Spain.
- Published Article
Chemistry & Biology
- Publication Date
May 01, 2005
In this issue of Chemistry & Biology, Francisco Malpartida and colleagues  report the formation of novel polyene amide derivatives upon transformation of the producer strain with SCP2*-derived vectors carrying the erythromycin resistance gene ermE. This unexpected finding provides a new tool for generating antifungal drugs by biotransformation.
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This record was last updated on 06/08/2018 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/15911369