Affordable Access

Gene frequency analysis of chromosomal initiation sites in Bacillus subtilis after ultraviolet light or x-ray exposure.

Authors
  • Billen, D
  • Hellerman, G
  • Carreira, L
Type
Published Article
Journal
Journal of bacteriology
Publication Date
Jan 01, 1972
Volume
109
Issue
1
Pages
379–384
Identifiers
PMID: 4621630
Source
Medline
License
Unknown

Abstract

Bacillus subtilis was exposed to ultraviolet light (UV) or X rays, and gene frequency analysis was used to study the location of initiation sites of postirradiation deoxyribonucleic acid (DNA) synthesis. It was found that DNA synthesis resumes primarily from the origin after UV exposure. With X irradiation, the origin is not selectively replicated. Elevated origin-to-terminal marker ratios observed after UV exposure of exponentially growing cells were interpreted as evidence for selective UV resistance of the replicative origin region of the bacterial chromosome.

Report this publication

Statistics

Seen <100 times