Affordable Access

Access to the full text

Gene expression of TMEM178, which encodes a negative regulator of NFATc1, decreases with the progression of asthma severity

Authors
  • Patel, Naiya B.1
  • Ostilla, Lorena A.1
  • Cuervo-Pardo, Lyda2
  • Berdnikovs, Sergejs1
  • Chiarella, Sergio E.1
  • 1 Northwestern University Feinberg School of Medicine, 211 East Ontario Street, Suite 1000, Chicago, IL, 60611, USA , Chicago (United States)
  • 2 University of Florida, Gainesville, USA , Gainesville (United States)
Type
Published Article
Journal
Clinical and Translational Allergy
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Aug 08, 2019
Volume
9
Issue
1
Identifiers
DOI: 10.1186/s13601-019-0280-9
Source
Springer Nature
Keywords
License
Green

Abstract

In two independent microarray studies involving primary airway epithelial cells, the relative gene expression of TMEM178 decreases with the progression of asthma severity. Our manuscript creates a paradigm for future studies dissecting the role of Tmem178 in the pathogenesis of severe asthma.

Report this publication

Statistics

Seen <100 times