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Gene expression profile is associated with chemoradiation resistance in rectal cancer.

Authors
  • Gantt, G A
  • Chen, Y
  • Dejulius, K
  • Mace, A G
  • Barnholtz-Sloan, J
  • Kalady, M F
Type
Published Article
Journal
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
Publication Date
Jan 01, 2014
Volume
16
Issue
1
Pages
57–66
Identifiers
DOI: 10.1111/codi.12395
PMID: 24034224
Source
Medline
Keywords
License
Unknown

Abstract

Certain rectal cancer gene profiles are associated with poor response to CRT. Alterations in the DNA double-strand break repair pathway could contribute to treatment resistance and provides an opportunity for further studies.

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