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Gene delivery to periodontal tissue using Bubble liposomes and ultrasound.

Authors
  • Sugano, M
  • Negishi, Y
  • Endo-Takahashi, Y
  • Hamano, N
  • Usui, M
  • Suzuki, R
  • Maruyama, K
  • Aramaki, Y
  • Yamamoto, M
Type
Published Article
Journal
Journal of Periodontal Research
Publisher
Wiley (Blackwell Publishing)
Publication Date
Jun 01, 2014
Volume
49
Issue
3
Pages
398–404
Identifiers
DOI: 10.1111/jre.12119
PMID: 23889504
Source
Medline
Keywords
License
Unknown

Abstract

From these results, the combination of Bubble liposomes and ultrasound provides an efficient technique for delivering plasmid DNA into the gingiva. This technique can be applied for the delivery of a variety of therapeutic molecules into target tissue, and may serve as a useful treatment strategy for periodontitis.

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