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Gastroduodenal, intestinal and colonic permeability during anticancer therapy.

Authors
  • Melichar, Bohuslav
  • Hyspler, Radomír
  • Kalábová, Hana
  • Dvorák, Josef
  • Tichá, Alena
  • Zadák, Zdenek
Type
Published Article
Journal
Hepato-gastroenterology
Publication Date
Jan 01, 2011
Volume
58
Issue
109
Pages
1193–1199
Identifiers
DOI: 10.5754/hge08101
PMID: 21937377
Source
Medline
License
Unknown

Abstract

An increase in gastroduodenal and intestinal permeability was observed in patients treated with bevacizumab, oxaliplatin, 5-fluorouracil and leucovorin, but not in patients treated with cetuximab, irinotecan, 5-fluorouracil and leucovorin. No significant increase in colonic permeability was observed, but the present method was insufficient to detect colonic permeability in a significant proportion of patients.

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