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Gastric acid and serum gastrin secretion before and after bypass of the small intestine for morbid obesity.

Authors
Type
Published Article
Journal
Surgery, gynecology & obstetrics
Publication Date
Volume
142
Issue
4
Pages
521–523
Identifiers
PMID: 769199
Source
Medline

Abstract

Six obese patients undergoing end-to-side jejunoileal bypass had gastric acid output and serum gastrin measurements performed preoperatively and within three months postoperatively. Meat extract stimulated acid output was higher in obese than in normal patients. Following the bypass procedure, basal and meat extract stimulated acid output significantly decreased. Basal and meat extract stimulated serum gastrin levels did not change following bypass. These studies demonstrate that after a small intestinal bypass, acid output decreases. Gastrin plays no role in this change.

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