Affordable Access

Access to the full text

Gas transfer and hemolysis in an intravascular lung assist device using a PZT actuator

Authors
  • Hong, Chul-Un1
  • Kim, Jeong-Mi2
  • Kim, Min-Ho3
  • Kim, Seong-Jong4
  • Kang, Hyung-Sub5
  • Kim, Jin-Shang5
  • Kim, Gi-Beum5
  • 1 Chonbuk National University, Division of Biomedical Engineering, CHTD, Duckjin-dong 1ga, Jeonju, 561-756, South Korea , Jeonju (South Korea)
  • 2 Wonkwang University Dental Hospital, Department of Dentistry, Wonkwang University, Sinyong-dong, Iksan, 570-749, South Korea , Sinyong-dong, Iksan (South Korea)
  • 3 Chonbuk National University Medical Schools, Department of Thoracic and Cardiovascular Surgery, Duckjin-dong 1ga, Jeonju, 561-756, South Korea , Jeonju (South Korea)
  • 4 Chonbuk National University, Division of Chemical Engineering, Duckjin-dong 1ga, Jeonju, 561-756, South Korea , Jeonju (South Korea)
  • 5 Chonbuk National University, Department of Pharmacology, College of Veterinary Medicine, Duckjin-dong 1ga, Jeonju, 561-756, South Korea , Jeonju (South Korea)
Type
Published Article
Journal
International Journal of Precision Engineering and Manufacturing
Publisher
Korean Society for Precision Engineering
Publication Date
Jan 01, 2009
Volume
10
Issue
1
Pages
67–73
Identifiers
DOI: 10.1007/s12541-009-0010-7
Source
Springer Nature
Keywords
License
Yellow

Abstract

The purpose of this study was to investigate the effect of multiple mechanical forces in gas exchange and hemolysis in an intravascular lung assist device (IVLAD). Specific focus was given to the effect of membrane vibration. We designed the oscillatory type artificial lung assist device attached with a polyvinylidene fluoride sensor and a lead zirconate titanate (PZT) actuator (vibrator). Maximum oxygen transfer occurred at a frequency of 7 Hz for bovine blood and 35 Hz for distilled water. The normalized index of hemolysis oxygenator values for the circuit was 0.0014 g/mL for excitation of the PZT actuator with a sinusoidal 10-V wave and 0.0018 g/mL for a 50-V wave. The experiment results indicate effective performance in enhancing the gas transfer of the IVLAD. This novel hollow membrane filter IVLAD design demonstrates an acceptable level of gas exchange performance with an acceptable level of blood compatibility, and so it has potential as an implantable lung assist device for patients with acute respiratory distress syndrome.

Report this publication

Statistics

Seen <100 times