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Ganglioside GQ1b enhances anti-double-stranded DNA antibody and IgG production of PBMCs from patients with systemic lupus erythematosus.

Authors
  • Kanda, N
  • Watanabe, S
Type
Published Article
Journal
Journal of Allergy and Clinical Immunology
Publisher
Elsevier
Publication Date
Mar 01, 2000
Volume
105
Issue
3
Pages
532–540
Identifiers
PMID: 10719304
Source
Medline
License
Unknown

Abstract

These results suggest that GQ1b may polyclonally increase the production of IgG, including IgG anti-dsDNA antibody, in PBMCs from patients with SLE by promoting IL-6 and IL-10 production of T cells through the enhancement of their PKC activity.

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