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[Gangliocytic paraganglioma of the duodenum. Case report with immunocytochemical characterization].

Authors
  • Barten, M
  • Klöppel, G
Type
Published Article
Journal
Zentralblatt für allgemeine Pathologie u. pathologische Anatomie
Publication Date
Jan 01, 1990
Volume
136
Issue
1-2
Pages
181–187
Identifiers
PMID: 2327185
Source
Medline
License
Unknown

Abstract

Described in this paper are histological, electron-microscopic, and immunocytochemical findings recorded from a duodenal gangliocytic paraganglioma in a 21-year old man. The sessile polypoid tumor consisted of epithelial cells, neuroid spindle cells, and gangliocytic elements. Neurosecretory granules were detected by electron-microscopy in the epithelial cells. The neuroid spindle cells exhibited the ultrastructural feature of Schwann cells. The tumor was immunocytochemically characterized by the S-100-reactivity of the spindle cells and numerous PP-reactive epithelial cells. Gangliocytic paragangliomas of the duodenum are of benign behaviour and should be removed by local excision.

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