Affordable Access

Access to the full text

Fungal proteinaceous compounds with multiple biological activities

Authors
  • Ng, Tzi Bun1
  • Cheung, Randy Chi Fai1
  • Wong, Jack Ho1
  • Chan, Yau Sang2
  • Dan, Xiuli1
  • Pan, Wenliang1
  • Wang, Hexiang3
  • Guan, Suzhen4
  • Chan, Ki5
  • Ye, Xiuyun6, 7
  • Liu, Fang8
  • Xia, Lixin2
  • Chan, Wai Yee1
  • 1 The Chinese University of Hong Kong, School of Biomedical Sciences, Faculty of Medicine, Hong Kong, China , Hong Kong (China)
  • 2 Shenzhen University, State Key Laboratory of Respiratory Disease for Allergy at Shenzhen University, School of Medicine, Nanhai Ave 3688, Shenzhen, Guangdong, 518060, People’s Republic of China , Shenzhen (China)
  • 3 China Agricultural University, State Key Laboratory for Agrobiotechnology and Department of Microbiology, Beijing, 100193, China , Beijing (China)
  • 4 Xinjiang Medical University, Department of Social Medicine, College of Public Health, Urumqi, 830011, China , Urumqi (China)
  • 5 The University of Hong Kong, Prince Philip Dental Hospital, Biomedical and Tissue Engineering Research Group, Faculty of Dentistry, 34 Hospital Road, Hong Kong, China , Hong Kong (China)
  • 6 Fuzhou University, College of Biological Sciences and Technology, Fuzhou, Fujian, China , Fuzhou (China)
  • 7 Fujian Key Laboratory of Marine Enzyme Engineering, Fuzhou, Fujian, China , Fuzhou (China)
  • 8 Nankai University, Department of Microbiology, Tianjin, China , Tianjin (China)
Type
Published Article
Journal
Applied Microbiology and Biotechnology
Publisher
Springer-Verlag
Publication Date
Jun 23, 2016
Volume
100
Issue
15
Pages
6601–6617
Identifiers
DOI: 10.1007/s00253-016-7671-9
Source
Springer Nature
Keywords
License
Yellow

Abstract

Fungi comprise organisms like molds, yeasts and mushrooms. They have been used as food or medicine for a long time. A large number of fungal proteins or peptides with diverse biological activities are considered as antibacterial, antifungal, antiviral and anticancer agents. They encompass proteases, ribosome inactivating proteins, defensins, hemolysins, lectins, laccases, ribonucleases, immunomodulatory proteins, and polysaccharopeptides. The target of the present review is to update the status of the various bioactivities of these fungal proteins and peptides and discuss their therapeutic potential.

Report this publication

Statistics

Seen <100 times