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Functionality of the Tumor Suppressor microRNA-1 in Malignant Tissue and Cell Line Cells of Uterine Leiomyosarcoma.

Authors
  • Stope, Matthias B1
  • Cernat, Victor2
  • Kaul, Anne2
  • Diesing, Karoline2
  • Koensgen, Dominique2
  • Burchardt, Martin3
  • Mustea, Alexander2
  • 1 Department of Urology, University Medicine Greifswald, Greifswald, Germany [email protected] , (Germany)
  • 2 Department of Gynecology and Obstetrics, University Medicine Greifswald, Greifswald, Germany. , (Germany)
  • 3 Department of Urology, University Medicine Greifswald, Greifswald, Germany. , (Germany)
Type
Published Article
Journal
Anticancer Research
Publisher
International Institute of Anticancer Research
Publication Date
Mar 01, 2018
Volume
38
Issue
3
Pages
1547–1550
Identifiers
PMID: 29491084
Source
Medline
Keywords
License
Unknown

Abstract

Tumor suppressive mechanisms of miR-1, seem to be inhibited in uLMS SK-UT-1 cells, maybe as part of the malignant transformation process. Regardless of the microRNA's cellular functionality, miR-1 may represent a promising biomarker of diagnosis in uLMS therapy.

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