Affordable Access

deepdyve-link
Publisher Website

A functional variant of PTPN22 confers risk for Vogt-Koyanagi-Harada syndrome but not for ankylosing spondylitis.

Authors
  • Zhang, Qi1
  • Qi, Jian1
  • Hou, Shengping1
  • Du, Liping1
  • Yu, Hongsong1
  • Cao, Qingfeng1
  • Zhou, Yan1
  • Liao, Dan1
  • Kijlstra, Aize2
  • Yang, Peizeng1
  • 1 The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology and Chongqing Eye Institute, Chongqing, P. R. China. , (China)
  • 2 University Eye Clinic Maastricht, Maastricht, The Netherlands. , (Netherlands)
Type
Published Article
Journal
PLoS ONE
Publisher
Public Library of Science
Publication Date
Jan 01, 2014
Volume
9
Issue
5
Identifiers
DOI: 10.1371/journal.pone.0096943
PMID: 24816862
Source
Medline
License
Unknown

Abstract

The study showed that a functional variant of PTPN22 confers risk for VKH syndrome but not for AAU+AS+ in a Chinese Han population, which may be due to a modulation of the PTPN22 expression, PBMC proliferation and IL-10 production.

Report this publication

Statistics

Seen <100 times