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[Functional neuroimaging in patients with rapid cycling bipolar depression].

Authors
  • Benabarre, A
  • Vieta, E
  • Martín, F
  • Lomeña, F
Type
Published Article
Journal
Revista española de medicina nuclear
Publication Date
Aug 01, 2001
Volume
20
Issue
5
Pages
386–390
Identifiers
PMID: 11470074
Source
Medline
License
Unknown

Abstract

Bipolar patients with a rapid cycling clinical course constitute an interesting sub-group for studies focused on the pathophysiology of the disorder, since several switches can be studied by the investigators in a short period of time. At present, functional neuroimaging techniques, as SPECT and PET, may be used for the neurobiological study of affective disorders. Few longitudinal functional neuroimaging studies assessing the different phases of bipolar disorder have been carried out. However, the published data suggest an asymmetrical temporal lobe dysfunction in depressive and manic phases of bipolar depression. Further studies with larger samples of patients are needed in order to improve our knowledge of the pathophysiology of bipolar disorder.

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