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Functional coactivation map of the human brain.

Authors
Type
Published Article
Journal
Cerebral Cortex
Publisher
Oxford University Press (OUP)
Publication Date
Feb 22, 2008
Volume
18
Issue
11
Pages
2553–2559
Identifiers
DOI: 10.1093/cercor/bhn014
PMID: 18296434
PMCID: PMC2567424
Source
USPC - SET - SVS
License
Green

Abstract

Understanding the interactions among different brain regions is fundamental to our understanding of brain function. Here we describe a complete map of functional connections in the human brain derived by an automatic meta-analysis of 825 neuroimaging articles, representing 3402 experiments. The likelihood of a functional connection between regions was estimated by studying the interdependence of their "activity," as reported in each experiment, across all experiments. We obtained a dense coactivation map that recovers some fundamental principles of the brain's functional connectivity, such as the symmetric interhemispheric connections, and important functional networks, such as the fronto-parietal attention network, the resting state network and the motor network.

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