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Fulminant hepatic failure secondary to congestive heart failure.

Authors
  • Kisloff, B
  • Schaffer, G
Type
Published Article
Journal
The American journal of digestive diseases
Publication Date
Oct 01, 1976
Volume
21
Issue
10
Pages
895–900
Identifiers
PMID: 1015498
Source
Medline
License
Unknown

Abstract

An elderly female with an acute episode of congestive heart failure, unaccompanied by any periods of hypotension, developed fulminant hepatic failure with an accompanying coagulopathy. Attempts to establish an etiology for her acute hepatic insufficiency, other than cardiac failure, proved negative. Fulminant hepatic failure as a consequence of congestive heart failure, without prolonged periods of hypotension preceding alteration in hepatic function, has not heretofore been described. Liver function is adversely effected in congestive heart failure. Hepatic ammonia clearance is impaired in cardiac failure and may be diminished to the point of resulting in hepatic encephalopathy. Coagulopathy is a frequent concomitant of fulminant hepatic failure. Establishing a clear etiology for a coagulopathy in the face of concomitant liver disease is difficult, thus making any therapeutic intervention fraught with peril.

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