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Full-range polarization-sensitive swept-source optical coherence tomography by simultaneous transversal and spectral modulation.

Authors
  • Yamanari, Masahiro
  • Makita, Shuichi
  • Lim, Yiheng
  • Yasuno, Yoshiaki
Type
Published Article
Journal
Optics Express
Publisher
The Optical Society
Publication Date
Jun 21, 2010
Volume
18
Issue
13
Pages
13964–13980
Identifiers
DOI: 10.1364/OE.18.013964
PMID: 20588529
Source
Medline
License
Unknown

Abstract

Polarization-sensitive swept-source optical coherence tomography (PS-SS-OCT) is used to measure three-dimensional phase-retardation images of birefringent biological tissue in vivo. PS-SS-OCT with continuous source polarization modulation is used to multiplex the incident states of polarization in the signal frequency of each A-scan. Although it offers the advantage of measurement speed that is as high as that of standard SS-OCT, its disadvantage is low axial measurement range. To overcome this drawback, we employed the B-M-mode scan (BM-scan) method, which removes complex conjugate ambiguity by applying phase modulation along the transversal scanning direction. Since polarization modulation and BM-scan are applied in different scanning directions, these methods can be combined to make the optimum use of both full range and polarization-sensitive imaging. Phase fluctuations that cause measurement failure were numerically canceled before demodulating the B-scan oriented modulation. After removing complex conjugate artifacts, the axial measurement range was 5.35 mm, and the signal-to-conjugate ratio was 40.5 dB. We demonstrated retinal imaging using the PS-SS-OCT system with a frequency-swept laser at a center wavelength of 1064 nm and an axial resolution of 11.4 microm in tissue. Full-range polarization-sensitive retinal images showed characteristic birefringence of fibrous tissues such as retinal nerve fiber, sclera, and lamina cribrosa.

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