Affordable Access

deepdyve-link
Publisher Website

Frontispiece: asymmetric reduction of α-amino ketones with a KBH4 solution catalyzed by Chiral Lewis acids.

Authors
  • He, Peng
  • Zheng, Haifeng
  • Liu, Xiaohua
  • Lian, Xiangjin
  • Lin, Lili
  • Feng, Xiaoming
Type
Published Article
Journal
Chemistry - A European Journal
Publisher
Wiley (John Wiley & Sons)
Publication Date
Oct 13, 2014
Volume
20
Issue
42
Identifiers
DOI: 10.1002/chem.201484271
PMID: 25288170
Source
Medline
Keywords
License
Unknown

Abstract

Asymmetric Alkali Metal Borohydride Reduction Alkali metal borohydrides are mild, inexpensive, highly selective, and environmentally friendly reducing agents in organic chemistry. In their Communication on page 13482 ff., X. Feng et al. demonstrate an efficient enantioselective reduction of both secondary and primary α-amino ketones with potassium borohydride solution catalyzed by chiral N,N'-dioxide-metal complex catalysts. The catalytic system features a convenient operation and tolerance to water, without the need for basic additives.

Report this publication

Statistics

Seen <100 times