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[The frequency of structural abnormalities in the hypothalamo-pituitary region and their clinical significance in patients with growth hormone deficiency].

Authors
  • Kucharska, Anna
  • Bołtuć, Adam
  • Chojnacki, Jarosław
Type
Published Article
Journal
Pediatric Endocrinology Diabetes and Metabolism
Publisher
PROQURAT Andrzej Prokurat
Publication Date
Jan 01, 2010
Volume
16
Issue
3
Pages
142–147
Identifiers
PMID: 21092690
Source
Medline
License
Unknown

Abstract

1. The structural malformations of hypothalamo-pituitary region were found in 42% of patients. 2. The diagnosis of multihormonal hypopituitarism in a patient is connected with an increased risk of the presence of severe structural abnormalities in hypothalamo-pituitary region. 3. IGF-1 level and maximal GH secretion are negatively correlated with the presence of malformations of the hypothalamo-pituitary region.

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