Affordable Access

Free energy landscapes of DNA and its assemblies: perspectives from coarse-grained modelling

Authors
  • Ouldridge, T
  • Doye, J
  • Louis, A
  • Schreck, J
  • Romano, F
  • Harrison, R
  • Mosayebi, M
  • Engel, M
Publication Date
Jun 09, 2022
Source
Spiral - Imperial College Digital Repository
Keywords
License
Unknown

Abstract

This chapter will provide an overview of how characterising free energy landscapes can provide insights into the biophysical properties of DNA, as well as into the behaviour of the DNA assemblies used in the field of DNA nanotechnology. The landscapes for these complex systems are accessible through the use of accurate coarse-grained descriptions of DNA. Particular foci will be the landscapes associated with DNA self-assembly and mechanical deformation, where the latter can arise from either externally imposed forces or internal stresses.

Report this publication

Statistics

Seen <100 times