Affordable Access

Access to the full text

The Foxo and the hound: chasing the in vivo regulation of T cell populations during infection

Authors
  • Tait, Elia D1
  • Hunter, Christopher A1
  • 1 School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. [email protected]
Type
Published Article
Journal
Nature Immunology
Publisher
Springer Nature
Publication Date
May 01, 2009
Volume
10
Issue
5
Pages
457–458
Identifiers
DOI: 10.1038/ni0509-457
Source
Springer Nature
License
Yellow

Abstract

T cell expansion and contraction during the immune response to pathogens are regulated by a wide variety of cell-intrinsic and cell-extrinsic factors. A new study identifies a role for CTLA-4 signaling and activation of the Foxo3 transcription factor in modulating T cell populations.

Report this publication

Statistics

Seen <100 times