Affordable Access

Access to the full text

Four-Dimensional Flow Magnetic Resonance Imaging for Assessment of Velocity Magnitudes and Flow Patterns in The Human Carotid Artery Bifurcation: Comparison with Computational Fluid Dynamics

Authors
  • Ngo, Minh Tri1
  • Kim, Chul In2
  • Jung, Jinmu2, 3
  • Chung, Gyung Ho1
  • Lee, Dong Hwan2, 3
  • Kwak, Hyo Sung1
  • 1 (G.H.C.)
  • 2 (J.J.)
  • 3 Hemorheology Research Institute, Chonbuk National University, Jeon-ju 54896, Korea
Type
Published Article
Journal
Diagnostics
Publisher
MDPI
Publication Date
Dec 13, 2019
Volume
9
Issue
4
Identifiers
DOI: 10.3390/diagnostics9040223
PMID: 31847224
PMCID: PMC6963916
Source
PubMed Central
Keywords
License
Green

Abstract

Purpose: Knowledge of the hemodynamics in the vascular system is important to understand and treat vascular pathology. The present study aimed to evaluate the hemodynamics in the human carotid artery bifurcation measured by four-dimensional (4D) flow magnetic resonance imaging (MRI) as compared to computational fluid dynamics (CFD). Methods: This protocol used MRI data of 12 healthy volunteers for the 3D vascular models and 4D flow MRI measurements for the boundary conditions in CFD simulation. We compared the velocities measured at the carotid bifurcation and the 3D velocity streamlines of the carotid arteries obtained by these two methods. Results: There was a good agreement for both maximum and minimum velocity values between the 2 methods for velocity magnitude at the bifurcation plane. However, on the 3D blood flow visualization, secondary flows, and recirculation regions are of poorer quality when visualized through the 4D flow MRI. Conclusion: 4D flow MRI and CFD show reasonable agreement in demonstrated velocity magnitudes at the carotid artery bifurcation. However, the visualization of blood flow at the recirculation regions and the assessment of secondary flow characteristics should be enhanced for the use of 4D flow MRI in clinical situations.

Report this publication

Statistics

Seen <100 times