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Four flavanocoumarins from the leaves of Litsea coreana LEVL.

Authors
  • Tang, Wen-Jian
  • Zhang, Yi-Long
  • Xiao, Qing-Pin
  • Huang, Cheng
  • Jin, Yong
  • Li, Jun
Type
Published Article
Journal
Chemistry & Biodiversity
Publisher
Wiley (John Wiley & Sons)
Publication Date
Jun 01, 2013
Volume
10
Issue
6
Pages
1128–1132
Identifiers
DOI: 10.1002/cbdv.201200236
PMID: 23776028
Source
Medline
License
Unknown

Abstract

Two new flavanocoumarins, 1 and 2, together with phyllocoumarin (3) and epiphyllocoumarin (4), were isolated from the leaves of Litsea coreana LEVL. in Anhui Province, China. The structures of 1-4 were elucidated by spectroscopic methods. Biological tests revealed that 1-4 exhibited moderate anti-inflammatory activities through inhibition of TNF-α and IL-1 production in primary mouse peritoneal macrophages activated with lipopolysaccharides (LPS).

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