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Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer.

Authors
  • Kaurah, Pardeep
  • MacMillan, Andrée
  • Boyd, Niki
  • Senz, Janine
  • De Luca, Alessandro
  • Chun, Nicki
  • Suriano, Gianpaolo
  • Zaor, Sonya
  • Van Manen, Lori
  • Gilpin, Cathy
  • Nikkel, Sarah
  • Connolly-Wilson, Mary
  • Weissman, Scott
  • Rubinstein, Wendy S
  • Sebold, Courtney
  • Greenstein, Robert
  • Stroop, Jennifer
  • Yim, Dwight
  • Panzini, Benoit
  • McKinnon, Wendy
  • And 20 more
Type
Published Article
Journal
JAMA
Publisher
American Medical Association
Publication Date
Jun 06, 2007
Volume
297
Issue
21
Pages
2360–2372
Identifiers
PMID: 17545690
Source
Medline
License
Unknown

Abstract

Recurrent CDH1 mutations in families with hereditary diffuse gastric cancer are due to both independent mutational events and common ancestry. The presence of a founder mutation from Newfoundland is strongly supported.

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