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Formocresol mutagenicity following primary tooth pulp therapy: an in vivo study.

Authors
  • Zarzar, P A
  • Rosenblatt, A
  • Takahashi, C S
  • Takeuchi, P L
  • Costa Júnior, L A
Type
Published Article
Journal
Journal of Dentistry
Publisher
Elsevier
Publication Date
Sep 01, 2003
Volume
31
Issue
7
Pages
479–485
Identifiers
PMID: 12927459
Source
Medline
License
Unknown

Abstract

The results revealed that, from a statistical standpoint, formocresol is not mutagenic. However, further investigations are required, preferably with a larger sample, in patients needing more than one pulpotomy in order to observe whether an increase in the quantity of the drug would increase the quantity of chromosome aberrations and also to verify individual susceptibility to chromosome alterations with the use of formocresol.

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