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Formation of angiotensin III by angiotensin-converting enzyme.

Authors
  • A T Chiu
  • J W Ryan
  • J M Stewart
  • F E Dorer
Publication Date
Apr 01, 1976
Source
PMC
Keywords
Disciplines
  • Biology
License
Unknown

Abstract

Angiotensin III is formed from des-Asp1 -angiotensin I by angiotensin-converting enzyme. The Km (11 muM) of the reaction is one-third of that for the conversion of angiotensin I into angiotensin II. As suggested by the Km values, bradykinin, peptide BPP9a and angiotensins II and III are better inhibitors of the formation of angiotensin II than of the formation of angiotensin III.

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