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Follow-up analysis on the epidemic strains of Orientia tsutsugamushi in the first outbreak of scrub typhus in Henan Province, China.

Authors
  • Zhang, Lijuan1
  • Jin, Zhang
  • Xia, Shengli
  • Zhang, Jingshan
  • Li, Menglei
  • Fu, Xiuping
  • Luan, Mingchun
  • 1 Department of Rickettsiology, National Institute of Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China. [email protected] , (China)
Type
Published Article
Journal
The Southeast Asian journal of tropical medicine and public health
Publication Date
May 01, 2007
Volume
38
Issue
3
Pages
482–486
Identifiers
PMID: 17877223
Source
Medline
License
Unknown

Abstract

To obtain knowledge of the genetic characteristics and types of the epidemic strains of Orientia tsutsugamushi in the first outbreak of scrub typhus in Henan Province, genus and type-specific primers were employed to amplify a fragment of the gene of 56 kDa protein. Serotyping demonstrated that, of the 19 patients [15 patients in recovery phase (10-40 days) and 4 of patients in acute phase (1-7 days)], 4 were infected with Gilliam type, 8 with Kato type, 6 with Karp type, and 1 with an unknown type. Successful genotyping was obtained for only 3 patients, indicating that 2 were infected with Karp type and 1 with Taiwan Kato type. Thus the outbreak of scrub typhus in Henan Province was caused by at least two epidemic strains.

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