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FMS-like tyrosine kinase 3 internal tandem duplication and the patterns of its gene sequence in 207 Chinese patients with de novo acute myeloid leukemia.

Authors
  • Zhong, Ling
  • Jia, Yong Qian
  • Meng, Wen Tong
  • Ni, Xun
Type
Published Article
Journal
Archives of Pathology & Laboratory Medicine
Publisher
Archives of Pathology and Laboratory Medicine
Publication Date
Jan 01, 2012
Volume
136
Issue
1
Pages
84–89
Identifiers
DOI: 10.5858/arpa.2010-0700-OA
PMID: 22208491
Source
Medline
License
Unknown

Abstract

Detection of FLT3 mutation is fast, easy, and inexpensive. The mutant to wild-type ratio is helpful for performing detailed risk stratification. DNA sequence analysis is more precise for confirming and evaluating the mutation pattern.

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