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Fluoxetine, amitriptyline and the electroencephalogram.

Authors
  • Tarn, M
  • Edwards, J G
  • Sedgwick, E M
Type
Published Article
Journal
Journal of Affective Disorders
Publisher
Elsevier
Publication Date
Sep 01, 1993
Volume
29
Issue
1
Pages
7–10
Identifiers
PMID: 8254147
Source
Medline
License
Unknown

Abstract

Electroencephalograms recorded before and after 4 weeks treatment of depressed patients with fluoxetine or amitriptyline were assessed visually and by power spectrum analysis blind to patient, treatment and whether the recordings were carried out before or after treatment. No significant between-group differences in alpha, beta or theta activity were found on visual assessment. Power spectrum analysis revealed a significant decrease in the amount of beta activity at week 4. There was no EEG evidence of drowsiness or epileptiform activity in either of the treatment groups.

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