In conclusion, data showed that fluoxetine alone and in the absence of serotonin acutely up-regulated Cx43 expression in astrocytes that can be assumed in molecular target therapy of MS patients. It seems that cAMP involvement in fluoxetine effects need more researches.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/25436087