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Fluoxetin upregulates connexin 43 expression in astrocyte.

Authors
  • Mostafavi, Hossein
  • Khaksarian, Mojtaba
  • Joghataei, Mohammad Taghi
  • Hassanzadeh, Gholamreza
  • Soleimani, Masoud
  • Eftekhari, Sanaz
  • Soleimani, Mansooreh
  • Mousavizadeh, Kazem
  • Hadjighassem, Mahmoud Reza
Type
Published Article
Journal
Basic and clinical neuroscience
Publication Date
Jan 01, 2014
Volume
5
Issue
1
Pages
74–79
Identifiers
PMID: 25436087
Source
Medline
Keywords
License
Unknown

Abstract

In conclusion, data showed that fluoxetine alone and in the absence of serotonin acutely up-regulated Cx43 expression in astrocytes that can be assumed in molecular target therapy of MS patients. It seems that cAMP involvement in fluoxetine effects need more researches.

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