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Fluorescence polarization spectroscopy and time-resolved fluorescence kinetics of native cancerous and normal rat kidney tissues.

Authors
  • Tata, D B
  • Foresti, M
  • Cordero, J
  • Tomashefsky, P
  • Alfano, M A
  • Alfano, R R
Type
Published Article
Journal
Biophysical journal
Publication Date
Sep 01, 1986
Volume
50
Issue
3
Pages
463–469
Identifiers
PMID: 3489490
Source
Medline
License
Unknown

Abstract

Steady state fluorescence polarization spectra and time-resolved emission decay kinetics have been measured in vitro from malignant and normal rat kidney tissue. The degrees of polarization and emission lifetimes from the cancerous and normal systems are different. The spectroscopic differences are attributed to environmental transformations local to the native flavin and porphyrin fluorophors' binding sites.

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