Solution processable semiconductor oxides have opened a new paradigm for theenhancement of the lifetime of thin film solar cells. Their fabrication by low-costand environmentally friendly solution-processable methods makes them ideal barrier(hole and electron) transport layers. In this work, we fabricate flexible ITO-freeorganic solar cells (OPV) by printing methods applying an aqueous solution-processedV2O5 as the hole transport layer (HTL) and compared them to devices applyingPEDOT:PSS. The transparent conducting electrode was PET/Ag/PEDOT/ZnO, andthe OPV configurationwas PET/Ag/PEDOT/ZnO/P3HT:PC60BM/HTL/Ag. Outdoorstability analyses carried out for more than 900 h revealed higher stability for devicesfabricated with the aqueous solution-processed V2O5.