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First trimester pregnancy loss associated with varicella zoster virus infection: histological definition of a case.

Authors
  • Oyer, C E
  • Cai, R
  • Coughlin, J J
  • Singer, D B
Type
Published Article
Journal
Human Pathology
Publisher
Elsevier
Publication Date
Jan 01, 1998
Volume
29
Issue
1
Pages
94–95
Identifiers
PMID: 9445140
Source
Medline
License
Unknown

Abstract

Pathological demonstration of varicella infection in first trimester aborted tissue is reported. A 24-year-old primigravida manifested chickenpox infection about 38 days after her last menstrual period or at 24 days age of the embryo. The conceptus survived another 4 to 5 weeks. The macerated embryo and placental tissue revealed nuclear changes consistent with varicella infection. Immunohistochemical stains and electron microscopy were confirmatory.

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