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First detection and genome sequencing of SARS-CoV-2 in an infected cat in France.

Authors
  • Sailleau, Corinne1
  • Dumarest, Marine1
  • Vanhomwegen, Jessica2, 3
  • Delaplace, Manon1
  • Caro, Valerie2, 3
  • Kwasiborski, Aurélia2, 3
  • Hourdel, Véronique2, 3
  • Chevaillier, Patrick4
  • Barbarino, Alix5
  • Comtet, Loic6
  • Pourquier, Philippe6
  • Klonjkowski, Bernard1
  • Manuguerra, Jean-Claude2, 3
  • Zientara, Stephan1
  • Le Poder, Sophie1
  • 1 UMR VIROLOGIE, INRAE, Ecole Nationale Vétérinaire d'Alfort, ANSES, Laboratoire de santé animale, Université Paris-Est, Maisons-Alfort, France. , (France)
  • 2 Environment and Infectious Risk Unit, Laboratory for Urgent Response to Biological Threats, Institut Pasteur, Paris, France. , (France)
  • 3 The OIE Collaborating Centre for Detection and Identification in Humans of Emerging Animal Pathogens, Institut Pasteur, Paris, France. , (France)
  • 4 Clinique vétérinaire, Savigny sur Orge, France. , (France)
  • 5 CHUVA, Ecole Nationale Vétérinaire d'Alfort, Université Paris-Est, Maisons-Alfort, France. , (France)
  • 6 IDVET, Grabels, France. , (France)
Type
Published Article
Journal
Transboundary and emerging diseases
Publication Date
Nov 01, 2020
Volume
67
Issue
6
Pages
2324–2328
Identifiers
DOI: 10.1111/tbed.13659
PMID: 32500944
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

After its first description in Wuhan (China), SARS-CoV-2 the agent of coronavirus disease 2019 (COVID-19) rapidly spread worldwide. Previous studies suggested that pets could be susceptible to SARS-CoV-2. Here, we investigated the putative infection by SARS-CoV-2 in 22 cats and 11 dogs from owners previously infected or suspected of being infected by SARS-CoV-2. For each animal, rectal, nasopharyngeal swabs and serum were taken. Swabs were submitted to RT-qPCR assays targeting 2 genes of SARS-CoV-2. All dogs were tested SARS-CoV-2 negative. One cat was tested positive by RT-qPCR on rectal swab. Nasopharyngeal swabs from this animal were tested negative. This cat showed mild respiratory and digestive signs. Serological analysis confirms the presence of antibodies against the SARS-CoV-2 in both serum samples taken 10 days apart. Genome sequence analysis revealed that the cat SARS-CoV-2 belongs to the phylogenetic clade A2a like most of the French human SARS-CoV-2. This study reports for the first time the natural infection of a cat in France (near Paris) probably through their owners. There is currently no evidence that cats can spread COVID-19 and owners should not abandon their pets or compromise their welfare. © 2020 Blackwell Verlag GmbH.

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