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Fibrosis progression rates between chronic hepatitis B and C patients with elevated alanine aminotransferase levels.

Authors
  • Fujiwara, Akiko
  • Sakaguchi, Kohsaku
  • Fujioka, Shinichi
  • Iwasaki, Yoshiaki
  • Senoh, Tomonori
  • Nishimura, Mamoru
  • Terao, Masako
  • Shiratori, Yasushi
Type
Published Article
Journal
Journal of gastroenterology
Publication Date
Jan 01, 2008
Volume
43
Issue
6
Pages
484–491
Identifiers
DOI: 10.1007/s00535-008-2183-8
PMID: 18600393
Source
Medline
License
Unknown

Abstract

This paired-biopsy study of untreated chronic hepatitis B or C demonstrated that fibrosis progression occurred largely in patients with continuously elevated ALT levels even over a relatively short period, and that liver fibrosis might progress by one stage within an average of 4-5 years of follow-up in patients with elevated ALT of 70 IU/l or more.

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