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Fibrosis-associated single-nucleotide polymorphisms in TGFB1 and CAV1 are not associated with the development of nephrogenic systemic fibrosis.

Authors
  • Le, Long P
  • Garibyan, Lilit
  • Lara, Daniel
  • Finberg, Karin E
  • Iafrate, A John
  • Duncan, Lyn M
  • Kay, Jonathan
  • Nazarian, Rosalynn M
Type
Published Article
Journal
American Journal of Dermatopathology
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
May 01, 2013
Volume
35
Issue
3
Pages
351–356
Identifiers
DOI: 10.1097/DAD.0b013e31826c5508
PMID: 23051628
Source
Medline
License
Unknown

Abstract

We conclude that polymorphisms in the genes encoding TGFB1 and CAV1 previously associated with the development and progression of fibrosis in several organ systems are not associated with development of NSF in this cohort of patients with renal impairment after GCCA exposure.

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