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Fibrillary glomerulonephritis--a report of two cases.

Authors
  • Perry, G J
  • Lin, B P
  • Wyndham, R N
  • Kalowski, S
Type
Published Article
Journal
Australian and New Zealand journal of medicine
Publication Date
Jun 01, 1989
Volume
19
Issue
3
Pages
250–253
Identifiers
PMID: 2775045
Source
Medline
License
Unknown

Abstract

Two patients with an uncommon form of glomerulonephritis are described. The main clinical features were hematuria and proteinuria associated with normal renal function. The glomerular lesions consisted of mesangial hypercellularity and capillary wall thickening. Immunofluorescence was positive for IgG and C3 in both cases. Widespread deposition of microfibrils (mean diameters 17.0 nm and 18.4 nm) within mesangial areas and capillary basement membranes was seen on electron microscopy. Congo red staining for amyloid was negative. In both patients there was no evidence of underlying disease or extra-glomerular involvement and hence the disorder appeared to represent a primary glomerulonephritis.

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