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FGF23 concentrations vary with disease status in autosomal dominant hypophosphatemic rickets.

Authors
  • Imel, Erik A
  • Hui, Siu L
  • Econs, Michael J
Type
Published Article
Journal
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Publication Date
Apr 01, 2007
Volume
22
Issue
4
Pages
520–526
Identifiers
PMID: 17227222
Source
Medline
License
Unknown

Abstract

Elevated FGF23 concentrations are associated with hypophosphatemia in ADHR, and remission of the phenotype is associated with lower FGF23 concentrations. FGF23 has an opposite relationship with phosphate in ADHR compared with controls. We conclude that ADHR symptoms and disease severity likely fluctuate with FGF23 concentrations.

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