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Identification of <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> in biopsy specimens from patients with Crohn's disease identified by <i>in situ</i> hybridization

American Society for Microbiology
Publication Date
  • Med/07 Microbiologia E Microbiologia Clinica
  • Med/08 Anatomia Patologica
  • Medicine


Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract of unknown etiology. We report on the presence of cell wall-deficient Mycobacterium avium subsp. paratuberculosis in 35 of 48 paraffin-embedded tissue specimens from 33 patients with Crohn's disease by in situ hybridization with IS900 as a probe.<br/> An erratum to this article can be found in: J. Clin. Microbiol. 2002, 40(2), p. 739.

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