Affordable Access

Publisher Website

A prospective study of a new immunochemical fecal occult blood test in Korean patients referred for colonoscopy

Authors
Publisher
Elsevier Inc.
Publication Date
Volume
38
Issue
4
Identifiers
DOI: 10.1016/j.clinbiochem.2005.01.003
Keywords
  • Colorectal Cancers
  • Adenomas
  • Immunochemical Fecal Occult Blood Test
  • Diagnostic Validity
Disciplines
  • Chemistry
  • Medicine

Abstract

Abstract Objectives: The exquisite performance characteristics of an immunochemical fecal occult blood test (IFOBT) are well understood. We evaluated the diagnostic validity of a new IFOBT for colorectal neoplasia in patients undergoing colonoscopy and compared its results with two other commercially available IFOBTs. Design and methods: Eighty-five consecutive patients referred for colonoscopy were studied. We performed three different IFOBTs, namely, HM-Jack®, Instant-View®, and a newly developed OcculTech® on each fecal specimen. Results: OcculTech was easy to perform and had a sensitivity, specificity, and positive predictive value of 58.3%, 76.3%, and 27.9%, respectively, for the detection of colorectal cancers and ≥1 cm adenomas. OcculTech showed higher sensitivity than the automatic analyzer, HM-Jack. No improvement was obtained by combining tests. Conclusions: The OcculTech test had performance characteristics comparable to the two other IFOBTs. This study confirms the usefulness of the OcculTech test for colorectal neoplasia screening.

There are no comments yet on this publication. Be the first to share your thoughts.